Literature summary extracted from

Dastmalchi, K.; Ollilainen, V.; Lackman, P.; Gennaes, G.B.; Dorman, H.J.; Jaervinen, P.P.; Yli-Kauhaluoma, J.; Hiltunen, R.
Acetylcholinesterase inhibitory guided fractionation of Melissa officinalis L. (2009), Bioorg. Med. Chem., 17, 867-871.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.1.1.7	cis-rosmarinic acid	from extracts of Melissa officinalis leaves	Homo sapiens
3.1.1.7	Melissa officinalis leaf extract	most of the fractions show inhibitory activity and are more potent than the extract due to antagonistic and synergistic effects between various constituents within the plant extract, mass spectrometric analysis of the inhibitory extract fractions, overview	Homo sapiens
3.1.1.7	physostigmine	-	Homo sapiens
3.1.1.7	rosmarinic acid derivative	from extracts of Melissa officinalis leaves	Homo sapiens
3.1.1.7	trans-rosmarinic acid	from extracts of Melissa officinalis leaves	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.1.7	Homo sapiens	-	-	-

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
3.1.1.7	8	-	assay at	Homo sapiens

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Release 2023.1 (January 2023)