EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.14.11.8 | L-ascorbic acid | activates, but is not essentially required | Mus musculus |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
1.14.11.8 | additional information | construction of senescence marker protein-30/gluconolactonase knockout mice, which cannot synthesize L-ascorbate in vivo, the mutant mice nevertheless produce normal levels of carnitine when fed an L-ascorbate lacking diet | Mus musculus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.14.11.8 | mitochondrion | - |
Mus musculus | 5739 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.11.8 | N6,N6,N6-trimethyl-L-lysine + 2-oxoglutarate + O2 | Mus musculus | - |
3-hydroxy-N6,N6,N6-trimethyl-L-lysine + succinate + CO2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.11.8 | Mus musculus | Q91ZE0 | - |
- |
3.1.1.17 | Mus musculus | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.11.8 | N6,N6,N6-trimethyl-L-lysine + 2-oxoglutarate + O2 | - |
Mus musculus | 3-hydroxy-N6,N6,N6-trimethyl-L-lysine + succinate + CO2 | - |
? | |
3.1.1.17 | D-glucono-1,5-lactone + H2O | - |
Mus musculus | D-gluconate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.11.8 | 6-N-trimethyllysine dioxygenase | - |
Mus musculus |
1.14.11.8 | TMLD | - |
Mus musculus |
3.1.1.17 | senescence marker protein-30/gluconolactonase | - |
Mus musculus |
3.1.1.17 | SMP30/GNL | - |
Mus musculus |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.14.11.8 | metabolism | the enzyme catalyzes the first step in the biosynthesis of carnitine | Mus musculus |