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Literature summary extracted from

  • Morar, M.; Hoskins, A.A.; Stubbe, J.; Ealick, S.E.
    Formylglycinamide ribonucleotide amidotransferase from Thermotoga maritima: structural insights into complex formation (2008), Biochemistry, 47, 7816-7830.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.3.5.3 expression in Escherichia coli Thermotoga maritima

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
6.3.5.3 in complex with gene products PurQ and PurS, to 3.5 A resolution. The complex has a stoichiometry of 2:1:1 for components PurS:PurQ:PurL, respectively. The flexibility of the PurS dimer is involved in the activation of the complex and the formation of an ammonia channel Thermotoga maritima

Organism

EC Number Organism UniProt Comment Textmining
6.3.5.3 Thermotoga maritima Q9X0X3 isoform PurL
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6.3.5.3 0.037
-
 37°C Thermotoga maritima

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.5.3 5'-phosphoribosylformylglycinamide + ATP + L-glutamine + H2O
-
 Thermotoga maritima phosphoribosylformylglycinamidine + L-glutamate + ADP + phosphate
-
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