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Literature summary extracted from

  • Meshalkina, L.E.; Kochetov, G.A.; Brauer, J.; Huebner, G.; Tittmann, K.; Golbik, R.
    New evidence for cofactors amino group function in thiamin catalysis by transketolase (2008), Biochem. Biophys. Res. Commun., 366, 692-697.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.2.1.1 Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.2.1.1
-
 Saccharomyces cerevisiae

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.2.1.1 37
-
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.2.1.1 beta-hydroxypyruvate + ?
-
 Saccharomyces cerevisiae ?
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
2.2.1.1 additional information as opposed to the kinetically stabilized carbanion/enamine intermediate in transketolase when reconstituted with the native cofactor, 2-(1,2-dihydroxyethyl)-4'-monomethylaminothiamin diphosphate is rapidly released from the active centers during turnover and accumulates in the medium on a preparative scale Saccharomyces cerevisiae