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Literature summary extracted from

  • Hart, M.L.; Koehler, D.; Eckle, T.; Kloor, D.; Stahl, G.L.; Eltzschig, H.K.
    Direct treatment of mouse or human blood with soluble 5'-nucleotidase inhibits platelet aggregation (2008), Arterioscler. Thromb. Vasc. Biol., 28, 1477-1483.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.1.3.5 medicine mouse and human platelet aggregation is completely inhibited after treatment with Crotalus atrox 5'-nucleotidase (5 units/ml) via generation of increased levels of extracellular adenosine and subsequent adenosine receptor signaling Crotalus atrox

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.5 adenosine 5'-(alpha,beta-methylene)diphosphate specific inhibitor, complete inhibition at 0.5 mM Crotalus atrox

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.5 soluble
-
Crotalus atrox
-
-

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.5 Crotalus atrox
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.5 venom
-
Crotalus atrox
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.5 5'-AMP + H2O
-
Crotalus atrox adenosine + phosphate
-
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Synonyms

EC Number Synonyms Comment Organism
3.1.3.5 5'-NT
-
Crotalus atrox
3.1.3.5 CD73
-
Crotalus atrox
3.1.3.5 ecto-5'-NT
-
Crotalus atrox
3.1.3.5 ecto-5'-nucleotidase
-
Crotalus atrox