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Literature summary extracted from

  • van Pee, K.H.; Patallo, E.P.
    Flavin-dependent halogenases involved in secondary metabolism in bacteria (2006), Appl. Microbiol. Biotechnol., 70, 631-641.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.14.19.9 61100
-
-
Pseudomonas fluorescens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.19.9 tryptophan + FADH2 + Cl- + O2 + H+ Lentzea aerocolonigenes rebeccamycin biosynthesis 7-chloro-tryptophan + FAD + H2O
-
?
1.14.19.9 tryptophan + FADH2 + Cl- + O2 + H+ Pseudomonas fluorescens rebeccamycin biosynthesis 7-chloro-tryptophan + FAD + H2O
-
?
1.14.19.58 L-tryptophan + FADH2 + Cl- + O2 + H+ Streptomyces rugosporus pyrroindomycin biosynthesis 5-chloro-L-tryptophan + FAD + 2 H2O
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.9 Lentzea aerocolonigenes Q8KHZ8
-
-
1.14.19.9 Pseudomonas fluorescens Q4KAM7
-
-
1.14.19.58 Streptomyces rugosporus A4D0H5
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.9 tryptophan + FADH2 + Cl- + O2 + H+
-
Lentzea aerocolonigenes 7-chloro-tryptophan + FAD + H2O
-
?
1.14.19.9 tryptophan + FADH2 + Cl- + O2 + H+
-
Pseudomonas fluorescens 7-chloro-tryptophan + FAD + H2O
-
?
1.14.19.9 tryptophan + FADH2 + Cl- + O2 + H+ rebeccamycin biosynthesis Lentzea aerocolonigenes 7-chloro-tryptophan + FAD + H2O
-
?
1.14.19.9 tryptophan + FADH2 + Cl- + O2 + H+ rebeccamycin biosynthesis Pseudomonas fluorescens 7-chloro-tryptophan + FAD + H2O
-
?
1.14.19.58 L-tryptophan + FADH2 + Cl- + O2 + H+
-
Streptomyces rugosporus 5-chloro-L-tryptophan + FAD + 2 H2O
-
?
1.14.19.58 L-tryptophan + FADH2 + Cl- + O2 + H+ pyrroindomycin biosynthesis Streptomyces rugosporus 5-chloro-L-tryptophan + FAD + 2 H2O
-
?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.9 PrnA
-
Pseudomonas fluorescens
1.14.19.9 RebH
-
Lentzea aerocolonigenes
1.14.19.58 pyrH
-
Streptomyces rugosporus