Literature summary extracted from

Grujic, D.; Salido, E.C.; Shenoy, B.C.; Langman, C.B.; McGrath, M.E.; Patel, R.J.; Rashid, A.; Mandapati, S.; Jung, C.W.; Margolin, A.L.
Hyperoxaluria is reduced and nephrocalcinosis prevented with an oxalate-degrading enzyme in mice with hyperoxaluria (2009), Am. J. Nephrol., 29, 86-93.

Application

EC Number	Application	Comment	Organism
4.1.1.2	medicine	OxDc-CLEC reduces hyperoxaluria and ameliorates nephrocalcinosis and urolithiasis	Mus musculus

General Stability

EC Number	General Stability	Organism
4.1.1.2	crystallization of OxDc noticeably increases the enzyme's specific activity and broadenes its pH-activity profile at both acidic pH 3.0 and neutral pH 7.0	Mus musculus

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.1.1.2	Mus musculus	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.1.1.2	oxalate + H+	-	Mus musculus	formate + CO2	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
4.1.1.2	oxalate-decarboxylase	-	Mus musculus
4.1.1.2	OxDc-CLEC	commercial preparation	Mus musculus

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Release 2023.1 (January 2023)