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Literature summary extracted from
- Knockdown of berberine bridge enzyme by RNAi accumulates (S)-reticuline and activates a silent pathway in cultured California poppy cells (2007), Transgenic Res., 16, 363-375.
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 1.21.3.3 | additional information | knockdown of berberine bridge enzyme by RNAi via Agrobacterium tumefaciens transfection leads to accumulation of (S)-reticuline and activates a silent pathway in cultured California poppy cells, they also produced a methylated derivative of reticuline, laudanine, which can scarcely be detected in control cells, analysis of reticuline metabolites, overview | Eschscholzia californica |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.21.3.3 | (S)-reticuline + O2 | Eschscholzia californica | the enzyme is involved in the biosynthetic pathway for benzophenanthridine alkaloids in California poppy, Eschscholzia californica, cells, related alkaloids, overview | (S)-scoulerine + H2O2 | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.21.3.3 | Eschscholzia californica | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.21.3.3 | (S)-reticuline + O2 | - |
Eschscholzia californica | (S)-scoulerine + H2O2 | - |
? | |
| 1.21.3.3 | (S)-reticuline + O2 | the enzyme is involved in the biosynthetic pathway for benzophenanthridine alkaloids in California poppy, Eschscholzia californica, cells, related alkaloids, overview | Eschscholzia californica | (S)-scoulerine + H2O2 | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.21.3.3 | BBE | - |
Eschscholzia californica |
| 1.21.3.3 | berberine bridge enzyme | - |
Eschscholzia californica |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.21.3.3 | 30 | - |
assay at | Eschscholzia californica |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.21.3.3 | 8.9 | - |
assay at | Eschscholzia californica |
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Release 2023.1 (January 2023)
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