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Literature summary extracted from

  • Zhang, L.; Miyaki, K.; Araki, J.; Nakayama, T.; Muramatsu, M.
    The relation between nicotinamide N-methyltransferase gene polymorphism and plasma homocysteine concentration in healthy Japanese men (2007), Thromb. Res., 121, 55-58.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.1.1.1 pharmacology biomarkers for cardiovascular risk factors Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.1 Homo sapiens P40261
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.1 blood plasma
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.1.1.1 additional information
-
 association between A/G single nucleotide polymorphism of NNMT gene and total homocysteine concentration in plasma of Japanese man analyzed, genotyping by PCR followed by melting curve analysis, NNMT genotype not determined as a strong determinant of total homocysteine concentration in plasma, modifying effect on plasma homocysteine concentration not excluded Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.1 S-adenosyl-L-methionine + nicotinamide NNMT gene polymorphism as potential marker for cardiovascular risk factors Homo sapiens S-adenosyl-L-homocysteine + 1-methylnicotinamide
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.1 NNMT
-
 Homo sapiens