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The relation between nicotinamide N-methyltransferase gene polymorphism and plasma homocysteine concentration in healthy Japanese men

Zhang, L.; Miyaki, K.; Araki, J.; Nakayama, T.; Muramatsu, M.; Thromb. Res. 121, 55-58 (2007)

Data extracted from this reference:

Application
EC Number
Application
Commentary
Organism
2.1.1.1
pharmacology
biomarkers for cardiovascular risk factors
Homo sapiens
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.1.1.1
Homo sapiens
P40261
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.1.1.1
blood plasma
-
Homo sapiens
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
2.1.1.1
additional information
-
association between A/G single nucleotide polymorphism of NNMT gene and total homocysteine concentration in plasma of Japanese man analyzed, genotyping by PCR followed by melting curve analysis, NNMT genotype not determined as a strong determinant of total homocysteine concentration in plasma, modifying effect on plasma homocysteine concentration not excluded
Homo sapiens
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.1.1.1
S-adenosyl-L-methionine + nicotinamide
NNMT gene polymorphism as potential marker for cardiovascular risk factors
690123
Homo sapiens
S-adenosyl-L-homocysteine + 1-methylnicotinamide
-
-
-
?
Application (protein specific)
EC Number
Application
Commentary
Organism
2.1.1.1
pharmacology
biomarkers for cardiovascular risk factors
Homo sapiens
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.1.1.1
blood plasma
-
Homo sapiens
-
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
2.1.1.1
additional information
-
association between A/G single nucleotide polymorphism of NNMT gene and total homocysteine concentration in plasma of Japanese man analyzed, genotyping by PCR followed by melting curve analysis, NNMT genotype not determined as a strong determinant of total homocysteine concentration in plasma, modifying effect on plasma homocysteine concentration not excluded
Homo sapiens
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.1.1.1
S-adenosyl-L-methionine + nicotinamide
NNMT gene polymorphism as potential marker for cardiovascular risk factors
690123
Homo sapiens
S-adenosyl-L-homocysteine + 1-methylnicotinamide
-
-
-
?