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Literature summary extracted from

  • Soucy, K.G.; Lim, H.K.; Benjo, A.; Santhanam, L.; Ryoo, S.; Shoukas, A.A.; Vazquez, M.E.; Berkowitz, D.E.
    Single exposure gamma-irradiation amplifies xanthine oxidase activity and induces endothelial dysfunction in rat aorta (2007), Radiat. Environ. Biophys., 46, 179-186.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.17.3.2 additional information gama-irradiation induces enzyme expression Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.17.3.2 xanthine + H2O + O2 Rattus norvegicus production of superoxide radicals can be induced by gama-irradiation and contributes to oxidative stress and endothelial nitroredox imbalance with resultant endothelial dysfunction and altered vascular mechanics, mechanism and regulation, overview urate + H2O2
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Organism

EC Number Organism UniProt Comment Textmining
1.17.3.2 Rattus norvegicus
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male sprague-dawley rats
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.17.3.2 aorta
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Rattus norvegicus
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1.17.3.2 endothelial cell
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Rattus norvegicus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.3.2 xanthine + H2O + O2 production of superoxide radicals Rattus norvegicus urate + H2O2
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?
1.17.3.2 xanthine + H2O + O2 production of superoxide radicals can be induced by gama-irradiation and contributes to oxidative stress and endothelial nitroredox imbalance with resultant endothelial dysfunction and altered vascular mechanics, mechanism and regulation, overview Rattus norvegicus urate + H2O2
-
?