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Literature summary extracted from

  • Culpepper, L.; Kovalick, L.J.
    A review of the literature on the selegiline transdermal system: an effective and well-tolerated monoamine oxidase inhibitor for the treatment of depression (2008), Prim. Care Companion J. Clin. Psychiatry, 10, 25-30.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
1.4.3.4 medicine selegiline is an effective and well-tolerated monoamine oxidase inhibitor for the treatment of depression. The selegiline transdermal system provides several advantages compared to orally administered monoamine oxidase inhibitors, including minimal interaction with dietary tyramine and prolonged exposure to the parent compound, while offering a favorable side effect profile. Treatment at the lowest effective dose of 6 mg/24 hours can be administered without the need for dietary modifications Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.4 selegiline an effective and well-tolerated monoamine oxidase inhibitor for the treatment of depression Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.4 Homo sapiens
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