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Literature summary extracted from

  • Leitsch, D.; Kolarich, D.; Wilson, I.B.; Altmann, F.; Duchene, M.
    Nitroimidazole action in Entamoeba histolytica: a central role for thioredoxin reductase (2007), PLoS Biol., 5, e211.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.8.1.9 expression in Escherichia coli Entamoeba histolytica

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.8.1.9 metronidazole metronidazole-modified recombinant enzyme displays considerably reduced thioredoxin reductase activity. By reducing metronidazole, the enzyme renders itself and associated thiol-containing proteins vulnerable to adduct formation Entamoeba histolytica

Organism

EC Number Organism UniProt Comment Textmining
1.8.1.9 Entamoeba histolytica
-
-
-

Synonyms

EC Number Synonyms Comment Organism
1.8.1.9 thioredoxin reductase
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Entamoeba histolytica