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Literature summary extracted from

  • Leu, Y.L.; Hwang, T.L.; Hu, J.W.; Fang, J.Y.
    Anthraquinones from Polygonum cuspidatum as tyrosinase inhibitors for dermal use (2008), Phytother. Res., 22, 552-556.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.14.18.1 drug development commercial plant extracts containing anthraquinones are being increasingly used for pharmaceuticals, foods and cosmetics due to their wide therapeutic and pharmacological properties Agaricus bisporus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.18.1 anthraglycoside B anthraquinone, isolated from the root of Polygonum cuspidatum Agaricus bisporus
1.14.18.1 citreorosein anthraquinone, isolated from the root of Polygonum cuspidatum Agaricus bisporus
1.14.18.1 emodin anthraquinone, isolated from the root of Polygonum cuspidatum Agaricus bisporus
1.14.18.1 kojic acid
-
 Agaricus bisporus
1.14.18.1 additional information the ranking of the inhibitory potency is physcion > citreorosein = anthraglycoside B = emodin Agaricus bisporus
1.14.18.1 physcion anthraquinone, isolated from the root of Polygonum cuspidatum. Most potent tyrosinase inhibition among the four anthraquinones examined, which is comparable to kojic acid Agaricus bisporus

Organism

EC Number Organism UniProt Comment Textmining
1.14.18.1 Agaricus bisporus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.18.1 commercial preparation
-
 Agaricus bisporus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.18.1 L-dopa + 1/2 O2
-
 Agaricus bisporus L-dopaquinone + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.18.1 tyrosinase
-
 Agaricus bisporus