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Literature summary extracted from

  • Carpene, C.; Abello, V.; Iffiu-Soltesz, Z.; Mercier, N.; Feve, B.; Valet, P.
    Limitation of adipose tissue enlargement in rats chronically treated with semicarbazide-sensitive amine oxidase and monoamine oxidase inhibitors (2008), Pharmacol. Res., 57, 426-434.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.4 (E)-2-(4-fluorophenethyl)-3-fluoroallylamine
-
 Rattus norvegicus
1.4.3.4 additional information SSAO inhibition is not sufficient to impair fat deposition. Combined MAO and SSAO inhibition limits adiposity in non-obese as well as in obese rats Rattus norvegicus
1.4.3.4 Phenelzine
-
 Rattus norvegicus
1.4.3.21 Phenelzine
-
 Rattus norvegicus
1.4.3.21 Semicarbazide
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.4 Rattus norvegicus
-
-
-
1.4.3.21 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.4 adipocyte SSAO inhibition is not sufficient to impair fat deposition. Combined MAO and SSAO inhibition limits adiposity in non-obese as well as in obese rats Rattus norvegicus
-
1.4.3.21 adipocyte SSAO inhibition is not sufficient to impair fat deposition. However, combined monoamine oxidase (EC 1.4.3.4) inhibition and SSAO inhibition limits adiposity in non-obese as well as in obese rats Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.21 tyramine + H2O + O2
-
 Rattus norvegicus 4-hydroxyphenylethanal + NH3 + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.4 MAO
-
 Rattus norvegicus
1.4.3.4 monoamine oxidase
-
 Rattus norvegicus
1.4.3.21 semicarbazide-sensitive amine oxidase
-
 Rattus norvegicus
1.4.3.21 SSAO
-
 Rattus norvegicus