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Literature summary extracted from

  • Prevot, D.; Soltesz, Z.; Abello, V.; Wanecq, E.; Valet, P.; Unzeta, M.; Carpene, C.
    Prolonged treatment with aminoguanidine strongly inhibits adipocyte semicarbazide-sensitive amine oxidase and slightly reduces fat deposition in obese Zucker rats (2007), Pharmacol. Res., 56, 70-79.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.4.3.4 medicine aminoguanidine may be useful for treating obesity via its SSAO blocking properties Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.4 aminoguanidine complete impairment of SSAO activity produced by aminoguanidine-treatment in obese rats is likely responsible for a weak limitation of fat deposition. Aminoguanidine may be useful for treating obesity via its SSAO blocking properties Rattus norvegicus
1.4.3.21 aminoguanidine strongly inhibits adipocyte semicarbazide-sensitive amine oxidase and slightly reduces fat deposition in obese Zucker rats. Aminoguanidine may be useful for treating obesity via its SSAO blocking properties Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.4 Rattus norvegicus
-
-
-
1.4.3.21 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.4 adipocyte
-
 Rattus norvegicus
-
1.4.3.21 adipocyte
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.21 benzylamine + H2O + O2
-
 Rattus norvegicus benzaldehyde + NH3 + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.4 semicarbazide-sensitive amine oxidase
-
 Rattus norvegicus
1.4.3.21 semicarbazide-sensitive amine oxidase
-
 Rattus norvegicus
1.4.3.21 SSAO
-
 Rattus norvegicus