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Literature summary extracted from

  • Ahmad, R.; Srivastava, A.K.
    Inhibition of glutathione-S-transferase from Plasmodium yoelii by protoporphyrin IX, cibacron blue and menadione: implications and therapeutic benefits (2008), Parasitol. Res., 102, 805-807.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.5.1.18 2-methyl-1,4-naphthoquinone 3.9% to 43.2% inhibition at 0.025 mM to 0.2 mM Plasmodium yoelii
2.5.1.18 Cibacron blue 94.3% inhibition at 0.064 mM Plasmodium yoelii
2.5.1.18 protoporphyrin IX 31.3% to 85.6% inhibition at 0.00025 mM to 0.25 mM Plasmodium yoelii

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.5.1.18 cytosol
-
 Plasmodium yoelii 5829
-

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.18 Plasmodium yoelii Q7REH6
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.5.1.18
-
 Plasmodium yoelii

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.18 glutathione + 1-chloro-2,4-dinitrobenzene
-
 Plasmodium yoelii S-(2,4-dinitrophenyl)glutathione + HCl
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.5.1.18 glutathione S-transferase
-
 Plasmodium yoelii
2.5.1.18 GST1
-
 Plasmodium yoelii

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.5.1.18 0.0004
-
 Cibacron blue
-
 Plasmodium yoelii
2.5.1.18 0.013
-
 protoporphyrin IX
-
 Plasmodium yoelii
2.5.1.18 0.08
-
 2-methyl-1,4-naphthoquinone
-
 Plasmodium yoelii