Literature summary extracted from

Thangasamy, T.; Sittadjody, S.; Lanza-Jacoby, S.; Wachsberger, P.R.; Limesand, K.H.; Burd, R.
Quercetin selectively inhibits bioreduction and enhances apoptosis in melanoma cells that overexpress tyrosinase (2007), Nutr. Cancer, 59, 258-268.

Protein Variants

EC Number	Protein Variants	Comment	Organism
1.14.18.1	additional information	tyrosinase overexpressing clones	Agaricus bisporus

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.14.18.1	quercetin	decreases the rate of bioreduction to a greater degree in tyrosinase overexpressing clones	Agaricus bisporus

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.18.1	Agaricus bisporus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.14.18.1	commercial preparation	-	Agaricus bisporus	-

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
1.14.18.1	additional information	-	150 U/ml of tyrosinase	Agaricus bisporus

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.18.1	3,3',4',5,7-pentahydroxyflavone + 1/2 O2	quercetin	Agaricus bisporus	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.14.18.1	tyrosinase	-	Agaricus bisporus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)