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Literature summary extracted from

  • Kaszaki, J.; Palasthy, Z.; Erczes, D.; Racz, A.; Torday, C.; Varga, G.; Vecsei, L.; Boros, M.
    Kynurenic acid inhibits intestinal hypermotility and xanthine oxidase activity during experimental colon obstruction in dogs (2008), Neurogastroenterol. Motil., 20, 53-62.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.17.3.2 additional information colon obstruction induces a hyperdynamic circulatory reaction, significantly elevated the motility index and increased mucosal leucocyte accumulation and XOR activity, the increase in activity is counteracted by kynurenic acid Canis lupus familiaris

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.17.3.2 Kynurenic acid
-
 Canis lupus familiaris

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.17.3.2 xanthine + H2O + O2 Canis lupus familiaris
-
 urate + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.17.3.2 Canis lupus familiaris
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.17.3.2 colon
-
 Canis lupus familiaris
-
1.17.3.2 intestine
-
 Canis lupus familiaris
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.3.2 xanthine + H2O + O2
-
 Canis lupus familiaris urate + H2O2
-
 ?
1.17.3.2 xanthine + H2O + O2 production of superoxide radicals Canis lupus familiaris urate + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.17.3.2 xanthine oxidoreductase
-
 Canis lupus familiaris
1.17.3.2 XOR
-
 Canis lupus familiaris

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.17.3.2 7.4
-
 assay at Canis lupus familiaris