Any feedback?
Literature summary extracted from
- Isolation of tyrosinase inhibitors from Artocarpus heterophyllus and use of its extract as antibrowning agent (2008), Mol. Nutr. Food Res., 52, 1530-1538.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 1.14.18.1 | food industry | inhibitors have good potential as antibrowning agents to be applied in real food systems | Agaricus bisporus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.18.1 | 7-(2,4-dihydroxyphenyl)-4-hydroxy-2-(2-hydroxypropan-2-yl)-2,3-dihydrofuro(3,2-g)chromen-5-one | artocarpfuranol, isolated from the wood of Artocarpus heterophyllus, strong mushroom tyrosinase inhibitory activity | Agaricus bisporus |  |
| 1.14.18.1 | artocarpanone | isolated from the wood of Artocarpus heterophyllus, strong mushroom tyrosinase inhibitory activity | Agaricus bisporus | |
| 1.14.18.1 | artocarpesin | isolated from the wood of Artocarpus heterophyllus, strong mushroom tyrosinase inhibitory activity | Agaricus bisporus | |
| 1.14.18.1 | artocarpetin | isolated from the wood of Artocarpus heterophyllus | Agaricus bisporus | |
| 1.14.18.1 | artocarpin | isolated from the wood of Artocarpus heterophyllus | Agaricus bisporus | |
| 1.14.18.1 | brosimone I | isolated from the wood of Artocarpus heterophyllus | Agaricus bisporus | |
| 1.14.18.1 | carpachromene | isolated from the wood of Artocarpus heterophyllus | Agaricus bisporus | |
| 1.14.18.1 | cudraflavone B | isolated from the wood of Artocarpus heterophyllus | Agaricus bisporus | |
| 1.14.18.1 | cyanomaclurin | isolated from the wood of Artocarpus heterophyllus | Agaricus bisporus | |
| 1.14.18.1 | cycloartocarpesin | isolated from the wood of Artocarpus heterophyllus | Agaricus bisporus | |
| 1.14.18.1 | cycloartocarpin | isolated from the wood of Artocarpus heterophyllus | Agaricus bisporus | |
| 1.14.18.1 | dihydromorin | isolated from the wood of Artocarpus heterophyllus, strong mushroom tyrosinase inhibitory activity | Agaricus bisporus | |
| 1.14.18.1 | isoartocarpesin | isolated from the wood of Artocarpus heterophyllus, strong mushroom tyrosinase inhibitory activity | Agaricus bisporus | |
| 1.14.18.1 | kojic acid | well-known tyrosinase inhibitor | Agaricus bisporus | |
| 1.14.18.1 | additional information | antibrowning effects of Artocarpus heterophyllus extracts on fresh-cut apple slices tested | Agaricus bisporus | |
| 1.14.18.1 | norartocarpetin | isolated from the wood of Artocarpus heterophyllus, strong mushroom tyrosinase inhibitory activity | Agaricus bisporus | |
| 1.14.18.1 | steppogenin | isolated from the wood of Artocarpus heterophyllus, strong mushroom tyrosinase inhibitory activity | Agaricus bisporus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.18.1 | Agaricus bisporus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.18.1 | commercial preparation | - |
Agaricus bisporus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.14.18.1 | 3900 | - |
mushroom tyrosinase solution (200 U/ml) added in the mushroom tyrosinase inhibition assay | Agaricus bisporus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.18.1 | L-tyrosine + O2 + AH2 | - |
Agaricus bisporus | L-dopa + H2O + A | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.14.18.1 | polyphenol oxidase | - |
Agaricus bisporus |
| 1.14.18.1 | tyrosinase | - |
Agaricus bisporus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.14.18.1 | 6.8 | - |
mushroom tyrosinase inhibition assay at | Agaricus bisporus |
IC50 Value
| EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|---|
| 1.14.18.1 | additional information | - |
IC50-values above 1 mM for artocarpin, cycloartocarpin, and cycloartocarpesin | Agaricus bisporus | additional information | |
| 1.14.18.1 | 0.0005254 | - |
- |
Agaricus bisporus | artocarpesin | |
| 1.14.18.1 | 0.0005733 | - |
- |
Agaricus bisporus | steppogenin | |
| 1.14.18.1 | 0.0006628 | - |
- |
Agaricus bisporus | isoartocarpesin | |
| 1.14.18.1 | 0.001545 | - |
- |
Agaricus bisporus | artocarpanone | |
| 1.14.18.1 | 0.01035 | - |
- |
Agaricus bisporus | dihydromorin | |
| 1.14.18.1 | 0.04793 | - |
- |
Agaricus bisporus | artocarpfuranol | |
| 1.14.18.1 | 0.06028 | - |
- |
Agaricus bisporus | brosimone I | |
| 1.14.18.1 | 0.06873 | - |
- |
Agaricus bisporus | cyanomaclurin | |
| 1.14.18.1 | 0.0716 | - |
- |
Agaricus bisporus | kojic acid | |
| 1.14.18.1 | 0.09438 | - |
- |
Agaricus bisporus | carpachromene | |
| 1.14.18.1 | 0.1666 | - |
- |
Agaricus bisporus | cudraflavone B | |
| 1.14.18.1 | 0.2009 | - |
- |
Agaricus bisporus | artocarpetin | |
| 1.14.18.1 | 0.4647 | - |
- |
Agaricus bisporus | norartocarpetin | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
