Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Sawabe, K.; Yamamoto, K.; Harada, Y.; Ohashi, A.; Sugawara, Y.; Matsuoka, H.; Hasegawa, H.
    Cellular uptake of sepiapterin and push-pull accumulation of tetrahydrobiopterin (2008), Mol. Genet. Metab., 94, 410-416.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.153 N-acetylserotonin
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.153 cytosol
-
 Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.153 6-pyruvoyl-5,6,7,8-tetrahydropterin + NADPH Homo sapiens
-
 tetrahydrobiopterin + NADP+
-
 r
1.1.1.153 additional information Homo sapiens sepiapterin or dihydrobiopterin are the precursors of the tetrahydrobiopterin-salvage pathway, enzyme activity and pathway regulation in vivo, overview ?
-
 ?
1.1.1.153 sepiapterin + NADPH + H+ Homo sapiens cellular uptake of sepiapterin across the cell membrane results in an efficient accumulation of tetrahydrobiopterin, sepiapterin relocates across the plasma membrane via two distinct paths, the slower path connects to the cytosolic compartment, overview 7,8-dihydrobiopterin + NADP+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.153 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.153 HeLa cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.153 6-pyruvoyl-5,6,7,8-tetrahydropterin + NADPH
-
 Homo sapiens tetrahydrobiopterin + NADP+
-
 r
1.1.1.153 additional information sepiapterin or dihydrobiopterin are the precursors of the tetrahydrobiopterin-salvage pathway, enzyme activity and pathway regulation in vivo, overview Homo sapiens ?
-
 ?
1.1.1.153 sepiapterin + NADPH + H+
-
 Homo sapiens 7,8-dihydrobiopterin + NADP+
-
 r
1.1.1.153 sepiapterin + NADPH + H+ cellular uptake of sepiapterin across the cell membrane results in an efficient accumulation of tetrahydrobiopterin, sepiapterin relocates across the plasma membrane via two distinct paths, the slower path connects to the cytosolic compartment, overview Homo sapiens 7,8-dihydrobiopterin + NADP+
-
 r