EC Number | Cloned (Comment) | Organism |
---|---|---|
1.11.1.24 | expressed in Escherichia coli strain FB810 | Schizosaccharomyces pombe |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
1.11.1.24 | C169S | decreased activity | Schizosaccharomyces pombe |
1.11.1.24 | C48S | completely inactive | Schizosaccharomyces pombe |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.11.1.24 | H2O2 | high concentrations of H2O2 temporarily inactivate Tpx1 | Schizosaccharomyces pombe |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.11.1.24 | Schizosaccharomyces pombe | O74887 | - |
- |
EC Number | Oxidation Stability | Organism |
---|---|---|
1.11.1.24 | inactivation of Tpx1 by oxidation of its catalytic cysteine to a sulfinic acid is always preceded by a sulfinic acid form in a covalently linked dimer | Schizosaccharomyces pombe |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.11.1.24 | GSH-Sepharose 4B bead chromatography | Schizosaccharomyces pombe |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.11.1.24 | H2O2 + reduced dithiothreitol | - |
Schizosaccharomyces pombe | H2O + oxidized dithiothreitol | - |
? | |
1.11.1.24 | H2O2 + reduced thioredoxin | - |
Schizosaccharomyces pombe | H2O + oxidized thioredoxin | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.11.1.24 | dimer | - |
Schizosaccharomyces pombe |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.11.1.24 | 2-Cys peroxiredoxin | - |
Schizosaccharomyces pombe |
1.11.1.24 | TPx1 | - |
Schizosaccharomyces pombe |
1.11.1.24 | two-cysteine peroxiredoxin | - |
Schizosaccharomyces pombe |