EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.149 | apigenin | inhibitory effect on hepatic NADPH-dependent activity in decreasing order: fisetin > apigenin > naringenin > quercetin | Mus musculus | |
1.1.1.149 | Bromophenol blue | little effect on hepatic NADPH-dependent 20alpha-hydroxysteroid dehydrogenase, moderate inhibitor of hepatic NADH-dependent 20alpha-hydroxysteroid dehydrogenase activity | Mus musculus | |
1.1.1.149 | fisetin | inhibitory effect on hepatic NADPH-dependent activity in decreasing order: fisetin > apigenin > naringenin > quercetin | Mus musculus | |
1.1.1.149 | naringenin | inhibitory effect on hepatic NADPH-dependent activity in decreasing order: fisetin > apigenin > naringenin > quercetin | Mus musculus | |
1.1.1.149 | quercetin | inhibitory effect on hepatic NADPH-dependent activity in decreasing order: fisetin > apigenin > naringenin > quercetin | Mus musculus | |
1.1.1.149 | Sulfobromophthalein | little effect on hepatic NADPH-dependent 20alpha-hydroxysteroid dehydrogenase, potent inhibitor of hepatic NADH-dependent 20alpha-hydroxysteroid dehydrogenase activity | Mus musculus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.149 | Mus musculus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.1.149 | kidney | the enzyme catalyzing renal NADPH-dependent 20alpha-hydroxysteroid dehydrogenase activity is distinct from enzyme(s) catalyzing hepatic NADPH- and NADH-dependent 20alpha-hydroxysteroid dehydrogenase activities | Mus musculus | - |
1.1.1.149 | liver | the enzyme catalyzing renal NADPH-dependent 20alpha-hydroxysteroid dehydrogenase activity is distinct from enzyme(s) catalyzing hepatic NADPH- and NADH-dependent 20alpha-hydroxysteroid dehydrogenase activities | Mus musculus | - |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.1.1.149 | 6 | - |
renal NADH-dependent 20alpha-hydroxysteroid dehydrogenase | Mus musculus |
1.1.1.149 | 6.5 | - |
hepatic NADPH-dependent 20alpha-hydroxysteroid dehydrogenase | Mus musculus |
1.1.1.149 | 7.4 | - |
hepatic NADH-dependent 20alpha-hydroxysteroid dehydrogenase | Mus musculus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.149 | NADH | - |
Mus musculus | |
1.1.1.149 | NADPH | - |
Mus musculus |