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Literature summary extracted from

  • Hennebert, O.; Chalbot, S.; Alran, S.; Morfin, R.
    Dehydroepiandrosterone 7alpha-hydroxylation in human tissues: possible interference with type 1 11beta-hydroxysteroid dehydrogenase-mediated processes (2007), J. Steroid Biochem. Mol. Biol., 104, 326-333.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.29 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.29 hepatocyte
-
 Homo sapiens
-
1.14.14.29 liver
-
 Homo sapiens
-
1.14.14.29 skin activity is detected in keratinocytes of the spinous and granula layers, and to lesser extent in the basal layer and basal cell bodies. High activity in hair follicle associated cells Homo sapiens
-
1.14.14.29 tonsil CYP7B1 occurrs in trabecular stroma cells Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.29 dehydroepiandrosterone + NADPH + H+ + o2
-
 Homo sapiens 7alpha-hydroxy-dehydroepiandrosterone + NADP+ + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.29 CYP7B1
-
 Homo sapiens
1.14.14.29 cytochome P450 7B1
-
 Homo sapiens