Literature summary extracted from

Gunningham, S.P.; Currie, M.J.; Morrin, H.R.; Tan, E.Y.; Turley, H.; Dachs, G.U.; Watson, A.I.; Frampton, C.; Robinson, B.A.; Fox, S.B.
The angiogenic factor thymidine phosphorylase up-regulates the cell adhesion molecule P-selectin in human vascular endothelial cells and is associated with P-selectin expression in breast cancers (2007), J. Pathol., 212, 335-344.

Application

EC Number	Application	Comment	Organism
2.4.2.4	medicine	thymidine phosphorylase may be involved in up-regulating P-selectin expression in breast cancer cells, tumor cell thymidine phosphorylase correlates with tumor cell P-selectin but not with endothelial cell P-selectin in vascular endothelial cells	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.2.4	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.4.2.4	thymidine + phosphate	-	Homo sapiens	thymine + 2-deoxy-D-ribose 1-phosphate	-	r

Synonyms

EC Number	Synonyms	Comment	Organism
2.4.2.4	PD-ECGF	-	Homo sapiens
2.4.2.4	platelet-derived endothelial cell growth factor	-	Homo sapiens

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Release 2023.1 (January 2023)