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Literature summary extracted from
- Divergent associations of plasma choline and betaine with components of metabolic syndrome in middle age and elderly men and women (2008), J. Nutr., 138, 914-920.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 1.1.99.1 | medicine | population-based study, relation of plasma choline and betaine to smoking, physical activity, BMI, percent body fat, waist circumference, blood pressure, serum lipids and glucose | Homo sapiens |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.1.99.1 | mitochondrion | - |
Homo sapiens | 5739 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.99.1 | choline + acceptor | Homo sapiens | - |
betaine aldehyde + reduced acceptor | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.99.1 | Homo sapiens | Q8NE62 | - |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.1.99.1 | blood plasma | choline and betaine levels | Homo sapiens | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.1.99.1 | additional information | - |
population-based study, unfavorable cardiovascular risk factor profile associated with high choline and low betaine concentrations, choline and betaine associated in opposite directions with key components of metabolic syndrome, disruption of mitochondrial choline dehydrogenase pathway | Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.99.1 | choline + acceptor | - |
Homo sapiens | betaine aldehyde + reduced acceptor | - |
? | |
| 1.1.99.1 | choline + acceptor | relation of plasma choline and betaine to cardiovascular risk factors, mitochondrial choline dehydrogenase pathway | Homo sapiens | betaine aldehyde + reduced acceptor | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.1.99.1 | ChoDH | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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