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Literature summary extracted from

  • Choi, J.W.; Shin, C.Y.; Choi, M.S.; Yoon, S.Y.; Ryu, J.H.; Lee, J.C.; Kim, W.K.; El Kouni, M.H.; Ko, K.H.
    Uridine protects cortical neurons from glucose deprivation-induced death: possible role of uridine phosphorylase (2008), J. Neurotrauma, 25, 695-707.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.2.3 additional information UPase expression is up-regulated by glucose deprivation in mRNA as well as protein levels Mus musculus
2.4.2.3 additional information UPase expression is up-regulated by glucose deprivation in mRNA as well as protein levels Rattus norvegicus
2.4.2.3 uridine mRNA and protein levels are up-regulated by uridine Mus musculus
2.4.2.3 uridine mRNA and protein levels are up-regulated by uridine Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.2.3 5-(phenylthio)acyclouridine specific inhibitor Mus musculus
2.4.2.3 5-(phenylthio)acyclouridine specific inhibitor Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.3 Mus musculus
-
-
-
2.4.2.3 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.3 brain
-
 Mus musculus
-
2.4.2.3 brain
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.3 uridine + phosphate
-
 Mus musculus uracil + alpha-D-ribose 1-phosphate
-
 r
2.4.2.3 uridine + phosphate
-
 Rattus norvegicus uracil + alpha-D-ribose 1-phosphate
-
 r

Synonyms

EC Number Synonyms Comment Organism
2.4.2.3 UPase
-
 Mus musculus
2.4.2.3 UPase
-
 Rattus norvegicus