EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.2.5 | - |
Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.2.5 | benzimidazole | - |
Rattus norvegicus | |
2.3.2.5 | benzylimidazole | - |
Rattus norvegicus | |
2.3.2.5 | H-Gln-7-amido-4-methylcoumarin | substrate inhibition | Rattus norvegicus | |
2.3.2.5 | H-Gln-beta-naphthylamide | substrate inhibition | Rattus norvegicus | |
2.3.2.5 | imidazole | - |
Rattus norvegicus | |
2.3.2.5 | N-methylimidazole | - |
Rattus norvegicus | |
2.3.2.5 | PBD150 | - |
Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.2.5 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.3.2.5 | brain cortex | high expression of QC in neurons of several cell layers of the cortex and hippocampus | Rattus norvegicus | - |
2.3.2.5 | hippocampus | high expression of QC in neurons of several cell layers of the cortex and hippocampus | Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.2.5 | amyloid beta(3-40) | - |
Rattus norvegicus | pyroglutamyl-amyloid beta(3-40) + NH3 | - |
? | |
2.3.2.5 | Gln-Gln | - |
Rattus norvegicus | 5-oxoprolyl-Gln + NH3 | - |
? | |
2.3.2.5 | Gln-Gly | - |
Rattus norvegicus | 5-oxoprolyl-Gly + NH3 | - |
? | |
2.3.2.5 | H-Gln-7-amido-4-methylcoumarin | - |
Rattus norvegicus | 5-oxoprolyl-7-amido-4-methylcoumarin + NH3 | - |
? | |
2.3.2.5 | H-Gln-beta-naphthylamide | - |
Rattus norvegicus | 5-oxoprolyl-beta-naphthylamide + NH3 | - |
? | |
2.3.2.5 | H-Gln-Glu-OH | - |
Rattus norvegicus | 5-oxoprolyl-Glu-OH + NH3 | - |
? | |
2.3.2.5 | H-Gln-Gly-Pro-OH | - |
Rattus norvegicus | 5-oxoprolyl-Gly-Pro-OH + NH3 | - |
? | |
2.3.2.5 | H-Gln-Phe-Arg-His-NH2 | - |
Rattus norvegicus | 5-oxoprolyl-Phe-Arg-His-NH2 + NH3 | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.2.5 | glutaminyl cyclase | - |
Rattus norvegicus |
2.3.2.5 | QC | - |
Rattus norvegicus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.2.5 | 0.0001 | - |
PBD150 | pH 8.0, 30°C | Rattus norvegicus | |
2.3.2.5 | 0.0035 | - |
benzylimidazole | pH 8.0, 30°C | Rattus norvegicus | |
2.3.2.5 | 0.013 | - |
N-methylimidazole | pH 8.0, 30°C | Rattus norvegicus | |
2.3.2.5 | 0.116 | - |
imidazole | pH 8.0, 30°C | Rattus norvegicus | |
2.3.2.5 | 0.13 | - |
benzimidazole | pH 8.0, 30°C | Rattus norvegicus | |
2.3.2.5 | 1.3 | - |
H-Gln-beta-naphthylamide | pH 8.0, 30°C | Rattus norvegicus | |
2.3.2.5 | 4.5 | - |
H-Gln-7-amido-4-methylcoumarin | pH 8.0, 30°C | Rattus norvegicus |