Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Speiser, Z.; Fine, T.; Litinetsky, L.; Eliash, S.; Blaugrund, E.; Cohen, S.
    Differential behavioral syndrome evoked in the rats after multiple doses of SSRI fluoxetine with selective MAO inhibitors rasagiline or selegiline (2008), J. Neural Transm., 115, 107-116.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.4.3.4 medicine the monoamine oxidase inhibitor rasagiline may provide a much lower risk of serotonin syndrome than the monoamine oxidase inhibitor selegiline in parkinsonian patients treated with an serotonin reuptake inhibitor Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.4 rasagiline
-
 Rattus norvegicus
1.4.3.4 selegiline
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.4 Rattus norvegicus P19643
-
-
1.4.3.4 Rattus norvegicus P21396
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.4 brain
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.4 phenylethylamine + H2O + O2
-
 Rattus norvegicus 2-phenylethanal + NH3 + H2O2
-
 ?
1.4.3.4 serotonin + H2O + O2
-
 Rattus norvegicus (5-hydroxy-1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.4 MAO-A
-
 Rattus norvegicus
1.4.3.4 MAO-B
-
 Rattus norvegicus