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Literature summary extracted from
- Optimal determination of heart tissue 26S-proteasome activity requires maximal stimulating ATP concentrations (2007), J. Mol. Cell. Cardiol., 42, 265-269.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.6.1.5 | ATP | increasing ATP beyond the optimal range is inhibitory | Rattus norvegicus |  |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.6.1.5 | ATP | increasing ATP beyond the optimal range is inhibitory | Rattus norvegicus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.6.1.5 | ATP + H2O + polypeptide | Rattus norvegicus | - |
ADP + phosphate + unfolded polypeptide | - |
ir | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.6.1.5 | Rattus norvegicus | - |
male Sprague-Dawley rat | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.6.1.5 | proteins are extracted from heart tissue | Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.6.1.5 | heart | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.6.1.5 | ATP + H2O + polypeptide | - |
Rattus norvegicus | ADP + phosphate + unfolded polypeptide | - |
ir | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.6.1.5 | 26S-proteasome | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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