EC Number | Application | Comment | Organism |
---|---|---|---|
2.3.1.26 | pharmacology | the data suggest that antiatherosclerotic activity of licorice in hypercholesterolemic patients might be related with its ACAT inhibitory effects | Homo sapiens |
2.3.1.26 | pharmacology | the data suggest that antiatherosclerotic activity of licorice in hypercholesterolemic patients might be related with its ACAT inhibitory effects | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.26 | glabrol | - |
Homo sapiens | |
2.3.1.26 | glabrol | - |
Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.3.1.26 | microsome | - |
Rattus norvegicus | - |
- |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.26 | acyl-CoA + cholesterol | Homo sapiens | - |
CoA + cholesterol ester | - |
? | |
2.3.1.26 | acyl-CoA + cholesterol | Rattus norvegicus | - |
CoA + cholesterol ester | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.26 | Homo sapiens | - |
- |
- |
2.3.1.26 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.3.1.26 | Hep-G2 cell | - |
Homo sapiens | - |
2.3.1.26 | liver | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.26 | acyl-CoA + cholesterol | - |
Homo sapiens | CoA + cholesterol ester | - |
? | |
2.3.1.26 | acyl-CoA + cholesterol | - |
Rattus norvegicus | CoA + cholesterol ester | - |
? | |
2.3.1.26 | oleoyl-CoA + cholesterol | activity assay | Homo sapiens | ? | - |
? | |
2.3.1.26 | oleoyl-CoA + cholesterol | activity assay | Rattus norvegicus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.1.26 | ACAT | - |
Homo sapiens |
2.3.1.26 | ACAT | - |
Rattus norvegicus |
2.3.1.26 | acyl-coenzyme A: cholesterol acyltransferase | - |
Homo sapiens |
2.3.1.26 | acyl-coenzyme A: cholesterol acyltransferase | - |
Rattus norvegicus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.3.1.26 | 37 | - |
activity assay | Homo sapiens |
2.3.1.26 | 37 | - |
activity assay | Rattus norvegicus |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
2.3.1.26 | 0.0246 | - |
- |
Rattus norvegicus | glabrol | |
2.3.1.26 | 0.026 | - |
- |
Homo sapiens | glabrol |