EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.8.1.12 | N-benzyolxycarbonyl-L-glutamyl(-benzoyl)-L-Leu-Ala | glutathione analogue, ASC-I-74B, inhibition of parasite growth and trypanothione reductase activity | Leishmania amazonensis | |
1.8.1.12 | N-benzyolxycarbonyl-L-glutamyl(-benzoyl)-L-Leu-Gly | glutathione analogue, ASC-I-74A, inhibition of parasite growth and trypanothione reductase activity | Leishmania amazonensis | |
1.8.1.12 | N-benzyolxycarbonyl-L-glutamyl(-benzoyl)-L-Val-Ala | glutathione analogue, ASC-I-75B, inhibition of parasite growth and trypanothione reductase activity | Leishmania amazonensis | |
1.8.1.12 | N-benzyolxycarbonyl-L-glutamyl(-benzoyl)-L-Val-Gly | glutathione analogue, ASC-I-75A, inhibition of parasite growth and trypanothione reductase activity | Leishmania amazonensis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.8.1.12 | Leishmania amazonensis | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.1.12 | trypanothione + NADP+ | parasite soluble fraction | Leishmania amazonensis | trypanothione disulfide + NADPH + H+ | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.8.1.12 | trypanothione reductase | TR | Leishmania amazonensis |