Literature summary extracted from

Ajloo, D.; Saboury, A.A.; Haghi-Asli, N.; Ataei-Jafarai, G.; Moosavi-Movahedi, A.A.; Ahmadi, M.; Mahnam, K.; Namaki, S.
Kinetic, thermodynamic and statistical studies on the inhibition of adenosine deaminase by aspirin and diclofenac (2007), J. Enzyme Inhib. Med. Chem., 22, 395-406.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.5.4.4	Acetylsalicylic acid	-	Bos taurus
3.5.4.4	diclofenac	competitive at 27°C, uncompetitive at 37°C	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.5.4.4	Bos taurus	-	calf	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.5.4.4	commercial preparation	-	Bos taurus	-
3.5.4.4	intestine	mucosa, commercial preparation	Bos taurus	-

Synonyms

EC Number	Synonyms	Comment	Organism
3.5.4.4	ADA	-	Bos taurus

Temperature Optimum [°C]

EC Number	Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
3.5.4.4	27	37	assay at	Bos taurus

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
3.5.4.4	7.5	-	assay at	Bos taurus

Ki Value [mM]

EC Number	Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
3.5.4.4	additional information	-	additional information	kinetics and thermodynamic effects of inhibitors, QSAR analysis, overview	Bos taurus
3.5.4.4	0.03	-	diclofenac	pH 7.5, 37°C	Bos taurus
3.5.4.4	0.0428	-	Acetylsalicylic acid	pH 7.5, 27°C	Bos taurus
3.5.4.4	0.0564	-	diclofenac	pH 7.5, 27°C	Bos taurus
3.5.4.4	0.0968	-	Acetylsalicylic acid	pH 7.5, 37°C	Bos taurus

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Release 2023.1 (January 2023)