Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Dabir, S.; Dabir, P.; Somvanshi, B.
    The kinetics of inhibition of Vigna catjang cotyledon and buffalo liver arginase by L-proline and branched-chain amino acids (2006), J. Enzyme Inhib. Med. Chem., 21, 727-731.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.3.1 L-isoleucine
-
 Bos taurus
3.5.3.1 L-isoleucine
-
 Vigna catjang
3.5.3.1 L-leucine
-
 Bos taurus
3.5.3.1 L-leucine
-
 Vigna catjang
3.5.3.1 L-lysine
-
 Bos taurus
3.5.3.1 L-lysine
-
 Vigna catjang
3.5.3.1 L-ornithine
-
 Bos taurus
3.5.3.1 L-ornithine
-
 Vigna catjang
3.5.3.1 L-proline
-
 Bos taurus
3.5.3.1 L-proline
-
 Vigna catjang
3.5.3.1 L-valine
-
 Bos taurus
3.5.3.1 L-valine
-
 Vigna catjang

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.5.3.1 Mn2+ full activation after preincubation for 20 min at 55°C with 2 mM Mn2+ Bos taurus
3.5.3.1 Mn2+ full activation after preincubation for 8 min at 35°C with 0.6 mM Mn2+ Vigna catjang

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.3.1 L-arginine + H2O Bos taurus
-
 L-ornithine + urea
-
 ?
3.5.3.1 L-arginine + H2O Vigna catjang
-
 L-ornithine + urea
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.3.1 Bos taurus
-
-
-
3.5.3.1 Vigna catjang
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.3.1 ammonium sulfate precipitation, AH-Sepharose 4B column chromatography, and gel filtration Bos taurus
3.5.3.1 ammonium sulfate precipitation, AH-Sepharose 4B column chromatography, and gel filtration Vigna catjang

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.3.1 cotyledon
-
 Vigna catjang
-
3.5.3.1 liver
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.3.1 L-arginine + H2O
-
 Bos taurus L-ornithine + urea
-
 ?
3.5.3.1 L-arginine + H2O
-
 Vigna catjang L-ornithine + urea
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.3.1 L-arginine amidino hydrolase
-
 Bos taurus
3.5.3.1 L-arginine amidino hydrolase
-
 Vigna catjang

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.5.3.1 35
-
 shows highest activity after 8 min preincubation at 35°C Vigna catjang
3.5.3.1 55
-
 shows highest activity after 20 min preincubation at 55°C Bos taurus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.5.3.1 5.5
-
 L-proline
-
 Bos taurus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.5.3.1 2
-
-
 Bos taurus L-leucine
3.5.3.1 2
-
-
 Bos taurus L-lysine
3.5.3.1 2
-
-
 Bos taurus L-ornithine
3.5.3.1 2
-
-
 Bos taurus L-valine
3.5.3.1 2
-
-
 Bos taurus L-isoleucine
3.5.3.1 10
-
-
 Vigna catjang L-proline
3.5.3.1 70
-
-
 Bos taurus L-proline
3.5.3.1 70
-
 IC50 above 70 mM Vigna catjang L-leucine
3.5.3.1 70
-
 IC50 above 70 mM Vigna catjang L-lysine
3.5.3.1 70
-
 IC50 above 70 mM Vigna catjang L-ornithine
3.5.3.1 70
-
 IC50 above 70 mM Vigna catjang L-valine
3.5.3.1 70
-
 IC50 above 70 mM Vigna catjang L-isoleucine