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Literature summary extracted from

  • Ayaz, M.; Lodhi, M.A.; Riaz, M.; Ul-haq, A.; Malik, A.; Choudhary, M.I.
    Novel urease inhibitors from Daphne oleoids (2006), J. Enzyme Inhib. Med. Chem., 21, 527-529.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.5 7'-hydroxy-2,2'-dioxo-2H,2'H-6,8'-bichromen-7-yl alpha-L-mannopyranoside
-
 Canavalia ensiformis
3.5.1.5 7'-hydroxy-2,2'-dioxo-2H,2'H-6,8'-bichromen-7-yl alpha-L-mannopyranoside
-
 Sporosarcina pasteurii
3.5.1.5 7'-hydroxy-2,2'-dioxo-3'-[(2-oxo-2H-chromen-7-yl)oxy]-2H,2'H-8,8'-bichromen-7-yl alpha-D-glucopyranoside
-
 Canavalia ensiformis
3.5.1.5 7'-hydroxy-2,2'-dioxo-3'-[(2-oxo-2H-chromen-7-yl)oxy]-2H,2'H-8,8'-bichromen-7-yl alpha-D-glucopyranoside
-
 Sporosarcina pasteurii
3.5.1.5 7'-methoxy-2,2'-dioxo-3'-[(2-oxo-2H-chromen-7-yl)oxy]-2H,2'H-8,8'-bichromen-7-yl alpha-D-glucopyranoside
-
 Canavalia ensiformis
3.5.1.5 7'-methoxy-2,2'-dioxo-3'-[(2-oxo-2H-chromen-7-yl)oxy]-2H,2'H-8,8'-bichromen-7-yl alpha-D-glucopyranoside
-
 Sporosarcina pasteurii
3.5.1.5 7-hydroxy-2,2'-dioxo-2H,2'H-6,8'-bichromen-7'-yl alpha-L-mannopyranoside
-
 Canavalia ensiformis
3.5.1.5 7-hydroxy-2,2'-dioxo-2H,2'H-6,8'-bichromen-7'-yl alpha-L-mannopyranoside
-
 Sporosarcina pasteurii
3.5.1.5 7-[(7-methoxy-2-oxo-2H-chromen-3-yl)oxy]-2-oxo-2H-chromen-6-yl alpha-D-glucopyranoside
-
 Canavalia ensiformis
3.5.1.5 7-[(7-methoxy-2-oxo-2H-chromen-3-yl)oxy]-2-oxo-2H-chromen-6-yl alpha-D-glucopyranoside
-
 Sporosarcina pasteurii
3.5.1.5 8-hydroxy-3-[(6-hydroxy-2-oxo-2H-chromen-7-yl)oxy]-2-oxo-2H-chromen-7-yl beta-D-glucopyranoside
-
 Canavalia ensiformis
3.5.1.5 8-hydroxy-3-[(6-hydroxy-2-oxo-2H-chromen-7-yl)oxy]-2-oxo-2H-chromen-7-yl beta-D-glucopyranoside
-
 Sporosarcina pasteurii
3.5.1.5 Thiourea
-
 Canavalia ensiformis
3.5.1.5 Thiourea
-
 Sporosarcina pasteurii

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.5 Canavalia ensiformis
-
-
-
3.5.1.5 Sporosarcina pasteurii
-
-
-

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.5.1.5 0.01506
-
-
 Sporosarcina pasteurii Thiourea
3.5.1.5 0.01506
-
-
 Sporosarcina pasteurii 7'-hydroxy-2,2'-dioxo-2H,2'H-6,8'-bichromen-7-yl alpha-L-mannopyranoside
3.5.1.5 0.021
-
-
 Canavalia ensiformis Thiourea
3.5.1.5 0.02205
-
-
 Sporosarcina pasteurii 7-hydroxy-2,2'-dioxo-2H,2'H-6,8'-bichromen-7'-yl alpha-L-mannopyranoside
3.5.1.5 0.02417
-
-
 Sporosarcina pasteurii 7'-hydroxy-2,2'-dioxo-3'-[(2-oxo-2H-chromen-7-yl)oxy]-2H,2'H-8,8'-bichromen-7-yl alpha-D-glucopyranoside
3.5.1.5 0.0263
-
-
 Canavalia ensiformis 7-hydroxy-2,2'-dioxo-2H,2'H-6,8'-bichromen-7'-yl alpha-L-mannopyranoside
3.5.1.5 0.02901
-
-
 Sporosarcina pasteurii 8-hydroxy-3-[(6-hydroxy-2-oxo-2H-chromen-7-yl)oxy]-2-oxo-2H-chromen-7-yl beta-D-glucopyranoside
3.5.1.5 0.02939
-
-
 Canavalia ensiformis 7'-hydroxy-2,2'-dioxo-3'-[(2-oxo-2H-chromen-7-yl)oxy]-2H,2'H-8,8'-bichromen-7-yl alpha-D-glucopyranoside
3.5.1.5 0.0316
-
-
 Canavalia ensiformis 8-hydroxy-3-[(6-hydroxy-2-oxo-2H-chromen-7-yl)oxy]-2-oxo-2H-chromen-7-yl beta-D-glucopyranoside
3.5.1.5 0.03762
-
-
 Sporosarcina pasteurii 7'-methoxy-2,2'-dioxo-3'-[(2-oxo-2H-chromen-7-yl)oxy]-2H,2'H-8,8'-bichromen-7-yl alpha-D-glucopyranoside
3.5.1.5 0.04
-
-
 Canavalia ensiformis 7'-methoxy-2,2'-dioxo-3'-[(2-oxo-2H-chromen-7-yl)oxy]-2H,2'H-8,8'-bichromen-7-yl alpha-D-glucopyranoside
3.5.1.5 0.05527
-
-
 Sporosarcina pasteurii 7-[(7-methoxy-2-oxo-2H-chromen-3-yl)oxy]-2-oxo-2H-chromen-6-yl alpha-D-glucopyranoside
3.5.1.5 0.06191
-
-
 Canavalia ensiformis 7-[(7-methoxy-2-oxo-2H-chromen-3-yl)oxy]-2-oxo-2H-chromen-6-yl alpha-D-glucopyranoside
3.5.1.5 0.09367
-
-
 Canavalia ensiformis 7'-hydroxy-2,2'-dioxo-2H,2'H-6,8'-bichromen-7-yl alpha-L-mannopyranoside