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Literature summary extracted from

  • Sloboda, D.M.; Moss, T.J.; Li, S.; Matthews, S.G.; Challis, J.R.; Newnham, J.P.
    Expression of glucocorticoid receptor, mineralocorticoid receptor, and 11beta-hydroxysteroid dehydrogenase 1 and 2 in the fetal and postnatal ovine hippocampus: ontogeny and effects of prenatal glucocorticoid exposure (2008), J. Endocrinol., 197, 213-220.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.1.1.B40 medicine exposure of fetus to high levels of synthetic glucocorticoid may have long-lasting effects on the hippocampal expression of hypothalamic-pituitary-adrenal-related genes into adulthood Ovis aries
1.1.1.146 medicine exposure of fetus to high levels of synthetic glucocorticoid may have long-lasting effects on the hippocampal expression of hypothalamic-pituitary-adrenal-related genes into adulthood Ovis aries

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.B40 Ovis aries
-
-
-
1.1.1.146 Ovis aries
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-
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.B40 hippocampus of animals that received betamethasone as a fetus, or whose mothers received betamethasone during pregnancy. Adult animals demonstrate increased mineralocorticoid and 11beta-HSD2 mRNA levels Ovis aries
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1.1.1.146 hippocampus of animals that received betamethasone as a fetus, or whose mothers received betamethasone during pregnancy. Adult animals demonstrate increased mineralocorticoid and 11beta-HSD2 mRNA levels Ovis aries
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Synonyms

EC Number Synonyms Comment Organism
1.1.1.B40 11beta-HSD2
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 Ovis aries
1.1.1.B40 11beta-hydroxysteroid dehydrogenase 2
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 Ovis aries
1.1.1.146 11beta-HSD1
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 Ovis aries
1.1.1.146 11beta-hydroxysteroid dehydrogenase 1
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 Ovis aries