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Literature summary extracted from

  • Ray, T.K.; Cronan, J.E.
    Activation of long chain fatty acids with acyl carrier protein: demonstration of a new enzyme, acyl-acyl carrier protein synthetase, in Escherichia coli (1976), Proc. Natl. Acad. Sci. USA, 73, 4374-4378.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
6.2.1.20 Triton X-100 stimulates Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.2.1.20 0.013
-
 stearic acid
-
 Escherichia coli
6.2.1.20 0.015
-
 myristic acid palmitic acid Escherichia coli
6.2.1.20 0.02
-
 palmitoleic acid cis-vaccenic acid, oleic acid, linoleic acid Escherichia coli
6.2.1.20 0.025
-
 lauric acid
-
 Escherichia coli
6.2.1.20 0.1
-
 Decanoic acid
-
 Escherichia coli
6.2.1.20 0.166
-
 octanoic acid
-
 Escherichia coli

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.2.1.20 soluble
-
 Escherichia coli
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.2.1.20 Ca2+ requires high concentrations of both Ca2+ and Mg2+ Escherichia coli
6.2.1.20 Mg2+ requires high concentrations of both Ca2+ and Mg2+ Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.2.1.20 ATP + an acid + [acyl-carrier protein] Escherichia coli enzyme functions in the incorporation of fatty acids into phospholipid ?
-
 ?
6.2.1.20 additional information Escherichia coli possibly functions in the activation of free fatty acids into a form that can be transferred into phospholipid ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.2.1.20 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.2.1.20 ATP + an acid + [acyl-carrier protein] enzyme functions in the incorporation of fatty acids into phospholipid Escherichia coli ?
-
 ?
6.2.1.20 ATP + cis-vaccenic acid + [acyl-carrier protein]
-
 Escherichia coli AMP + diphosphate + cis-vaccenoyl-[acyl-carrier protein]
-
 ?
6.2.1.20 ATP + decanoic acid + [acyl-carrier protein]
-
 Escherichia coli AMP + diphosphate + decanoyl-[acyl-carrier protein]
-
 ?
6.2.1.20 ATP + lauric acid + [acyl-carrier protein]
-
 Escherichia coli AMP + diphosphate + lauroyl-[acyl-carrier protein]
-
 ?
6.2.1.20 ATP + linoleic acid + [acyl-carrier protein]
-
 Escherichia coli AMP + diphosphate + linoleoyl-[acyl-carrier protein]
-
 ?
6.2.1.20 ATP + myristic acid + [acyl-carrier protein]
-
 Escherichia coli AMP + diphosphate + myristoyl-[acyl-carrier protein]
-
 ?
6.2.1.20 ATP + octanoic acid + [acyl-carrier protein]
-
 Escherichia coli AMP + diphosphate + octanoyl-[acyl-carrier protein]
-
 ?
6.2.1.20 ATP + oleic acid + [acyl-carrier protein]
-
 Escherichia coli AMP + diphosphate + oleoyl-[acyl-carrier protein]
-
 ?
6.2.1.20 ATP + palmitic acid + [acyl-carrier protein]
-
 Escherichia coli AMP + diphosphate + palmitoyl-[acyl-carrier protein]
-
 ?
6.2.1.20 ATP + palmitoleic acid + [acyl-carrier protein]
-
 Escherichia coli AMP + diphosphate + palmitoleoyl-[acyl-carrier protein]
-
 ?
6.2.1.20 ATP + stearic acid + [acyl-carrier protein]
-
 Escherichia coli AMP + diphosphate + stearoyl-[acyl-carrier protein]
-
 ?
6.2.1.20 additional information possibly functions in the activation of free fatty acids into a form that can be transferred into phospholipid Escherichia coli ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
6.2.1.20 7.5 8.5
-
 Escherichia coli