EC Number | Crystallization (Comment) | Organism |
---|---|---|
3.5.4.1 | the crystal structure of cytosine deaminase combined with the substrate uracil, PDB ID code: 1P6O, optimization in the water solvent at the ONIOM molecular dynamics study, overview | Saccharomyces cerevisiae |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.4.1 | cytosine + H2O | Saccharomyces cerevisiae | - |
uracil + NH3 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.5.4.1 | Saccharomyces cerevisiae | Q12178 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.4.1 | cytosine + H2O | - |
Saccharomyces cerevisiae | uracil + NH3 | - |
? | |
3.5.4.1 | cytosine + H2O | - |
Saccharomyces cerevisiae | uracil + NH3 | uracil binding structure at the active site, analysis by ab initio ONIOM-MD simulations showing that uracil is strongly perturbed by Ile33, which sandwiches uracil with His62, through the steric contact due to the thermal motion, detailed overview | ? |