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Literature summary extracted from

  • Schneider, J.E.; Stork, L.A.; Bell, J.T.; Hove, M.T.; Isbrandt, D.; Clarke, K.; Watkins, H.; Lygate, C.A.; Neubauer, S.
    Cardiac structure and function during ageing in energetically compromised Guanidinoacetate N-methyltransferase (GAMT)-knockout mice - a one year longitudinal MRI study (2008), J. Cardiovasc. Magn. Reson., 10, 1-9.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
2.1.1.2 medicine since creatine plays an important role in the buffering and transfer of high-energy phosphate bonds in the heart, it is hypothesized that lack of creatine would be detrimental for resting cardiac performance during ageing Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.2 S-adenosyl-L-methionine + guanidinoacetate Mus musculus
-
 S-adenosyl-L-homocysteine + creatine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.2 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.2 heart
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.2 S-adenosyl-L-methionine + guanidinoacetate
-
 Mus musculus S-adenosyl-L-homocysteine + creatine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.2 GAMT
-
 Mus musculus
2.1.1.2 guanidinoacetate N-methyltransferase
-
 Mus musculus