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Literature summary extracted from

  • Hasegawa, T.; Hashimoto, K.; Kawasaki, H.; Nakamatsu, T.
    Changes in enzyme activities at the pyruvate node in glutamate-overproducing Corynebacterium glutamicum (2008), J. Biosci. Bioeng., 105, 12-19.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.2.1.105 expressed in Corynebacterium glutamicum Corynebacterium glutamicum

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.105 Corynebacterium glutamicum
-
 strain ATCC13869
-
1.2.1.105 Corynebacterium glutamicum ATCC 13869
-
 strain ATCC13869
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.105 2-oxoglutarate + CoA + 3-acetylpyridine adenine dinucleotide 3-acetylpyridine adenine dinucleotide is used instead of NAD+ to avoid concomitant oxidase activity that would degrade NADH produced by the ODH reaction Corynebacterium glutamicum succinyl-CoA + CO2 + reduced 3-acetylpyridine adenine dinucleotide
-
 ?
1.2.1.105 2-oxoglutarate + CoA + 3-acetylpyridine adenine dinucleotide 3-acetylpyridine adenine dinucleotide is used instead of NAD+ to avoid concomitant oxidase activity that would degrade NADH produced by the ODH reaction Corynebacterium glutamicum ATCC 13869 succinyl-CoA + CO2 + reduced 3-acetylpyridine adenine dinucleotide
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.105 2-oxoglutarate dehydrogenase
-
 Corynebacterium glutamicum
1.2.1.105 ODH
-
 Corynebacterium glutamicum

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.105 3-acetylpyridine adenine dinucleotide 3-acetylpyridine adenine dinucleotide can be used instead of NAD+ to avoid concomitant oxidase activity that would degrade NADH produced by the ODH reaction Corynebacterium glutamicum
1.2.1.105 NAD+
-
 Corynebacterium glutamicum