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Literature summary extracted from

  • Weaver, K.D.; Heymann, J.J.; Mehta, A.; Roulhac, P.L.; Anderson, D.S.; Nowalk, A.J.; Adhikari, P.; Mietzner, T.A.; Fitzgerald, M.C.; Crumbliss, A.L.
    Ga(3+) as a mechanistic probe in Fe(3+) transport - characterization of Ga (3+) interaction with FbpA (2008), J. Biol. Inorg. Chem., 13, 887-898.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
7.2.2.7 the FbpA gene from Neisseria gonorrhoeae strain F62 is cloned for expression of the protein in Escherichia coli cells Neisseria gonorrhoeae

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.2.2.7 Ga3+
-
 Haemophilus influenzae
7.2.2.7 gallium
-
 Neisseria gonorrhoeae
7.2.2.7 gallium
-
 Neisseria meningitidis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
7.2.2.7 34000
-
 FbpA Haemophilus influenzae
7.2.2.7 34000
-
 FbpA Neisseria gonorrhoeae
7.2.2.7 34000
-
 FbpA Neisseria meningitidis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.2.2.7 ATP + H2O + Fe3+/out Haemophilus influenzae shuttling of free Fe3+ through the periplasm ADP + phosphate + Fe3+/in
-
 ?
7.2.2.7 ATP + H2O + Fe3+/out Neisseria gonorrhoeae shuttling of free Fe3+ through the periplasm ADP + phosphate + Fe3+/in
-
 ?
7.2.2.7 ATP + H2O + Fe3+/out Neisseria meningitidis shuttling of free Fe3+ through the periplasm ADP + phosphate + Fe3+/in
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.2.2.7 Haemophilus influenzae
-
-
-
7.2.2.7 Neisseria gonorrhoeae
-
-
-
7.2.2.7 Neisseria meningitidis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
7.2.2.7 apo-FbpA is purified by cetyltrimethylammonium bromide extraction and by using a carboxymethyl Sepharose column Neisseria gonorrhoeae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.2.2.7 ATP + H2O + Fe3+/out shuttling of free Fe3+ through the periplasm Haemophilus influenzae ADP + phosphate + Fe3+/in
-
 ?
7.2.2.7 ATP + H2O + Fe3+/out shuttling of free Fe3+ through the periplasm Neisseria gonorrhoeae ADP + phosphate + Fe3+/in
-
 ?
7.2.2.7 ATP + H2O + Fe3+/out shuttling of free Fe3+ through the periplasm Neisseria meningitidis ADP + phosphate + Fe3+/in
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.2.2.7 Fe3+transporting ATPase
-
 Haemophilus influenzae
7.2.2.7 Fe3+transporting ATPase
-
 Neisseria gonorrhoeae
7.2.2.7 Fe3+transporting ATPase
-
 Neisseria meningitidis
7.2.2.7 hFbpABC transporter
-
 Haemophilus influenzae
7.2.2.7 hFbpABC transporter
-
 Neisseria gonorrhoeae
7.2.2.7 hFbpABC transporter
-
 Neisseria meningitidis