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Literature summary extracted from

  • Rush, J.S.; Gao, N.; Lehrman, M.A.; Waechter, C.J.
    Recycling of dolichyl monophosphate to the cytoplasmic leaflet of the endoplasmic reticulum after the cleavage of dolichyl pyrophosphate on the lumenal monolayer (2008), J. Biol. Chem., 283, 4087-4093.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.108 microsome phosphorylation of dolichol on cytoplasmic surface of calf microsomal vesicles to be activated for lipid intermediate synthesis Bos taurus
-
-
3.6.1.43 membrane
-
 Saccharomyces cerevisiae 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.43 dolichyl diphosphate + H2O Saccharomyces cerevisiae Dol-P produced by DPPase contributes significantly to the pool of Dol-P utilized for lipid intermediate biosynthesis on the cytoplasmic leaflet, dolichyl phosphate metabolism, overview dolichyl phosphate + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.108 Bos taurus
-
 calf
-
3.6.1.43 Saccharomyces cerevisiae
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.108 brain
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.108 CTP + dolichol
-
 Bos taurus CDP + dolichyl phosphate
-
 ?
3.6.1.43 dolichyl diphosphate + H2O Dol-P produced by DPPase contributes significantly to the pool of Dol-P utilized for lipid intermediate biosynthesis on the cytoplasmic leaflet, dolichyl phosphate metabolism, overview Saccharomyces cerevisiae dolichyl phosphate + phosphate
-
 ?
3.6.1.43 dolichyl diphosphate + H2O calf brain microsomes, sealed vesicles, are used as substrates Saccharomyces cerevisiae dolichyl phosphate + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.6.1.43 Dol-P-P phosphatase
-
 Saccharomyces cerevisiae
3.6.1.43 DPPase
-
 Saccharomyces cerevisiae

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.6.1.43 7.4
-
 assay at Saccharomyces cerevisiae

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.108 CTP
-
 Bos taurus