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Literature summary extracted from

  • Peskin, A.V.; Low, F.M.; Paton, L.N.; Maghzal, G.J.; Hampton, M.B.; Winterbourn, C.C.
    The high reactivity of peroxiredoxin 2 with H(2)O(2) is not reflected in its reaction with other oxidants and thiol reagents (2007), J. Biol. Chem., 282, 11885-11892.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.11.1.24 21805
-
 1 * 21805, electrospray ionization mass spectrometry Homo sapiens
1.11.1.24 21810
-
 electrospray ionization mass spectrometry Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.24 Homo sapiens P32119
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.11.1.24 HiPrep 16/10 DEAE column chromatography Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.11.1.24 erythrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.24 cumene hydroperoxide + reduced dithiothreitol low activity Homo sapiens 2-phenylpropan-2-ol + oxidized dithiothreitol
-
 ?
1.11.1.24 glycine chloramine + dithiothreitol slow reaction Homo sapiens ?
-
 ?
1.11.1.24 H2O2 + reduced dithiothreitol reduced Prx2 is exceptionally reactive withH2O2 and other peroxides but shows very low reactivity with other thiol oxidants and alkylating agents Homo sapiens H2O + oxidized dithiothreitol
-
 ?
1.11.1.24 histamine chloramine + dithiothreitol slow reaction Homo sapiens ?
-
 ?
1.11.1.24 HOCl + dithiothreitol low activity Homo sapiens ?
-
 ?
1.11.1.24 monochloramine + dithiothreitol slow reaction Homo sapiens ?
-
 ?
1.11.1.24 taurine chloramine + dithiothreitol slow reaction Homo sapiens ?
-
 ?
1.11.1.24 tert-butyl hydroperoxide + reduced dithiothreitol low activity Homo sapiens tert-butanol + oxidized dithiothreitol
-
 ?

Subunits

EC Number Subunits Comment Organism
1.11.1.24 monomer 1 * 21805, electrospray ionization mass spectrometry Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
1.11.1.24 peroxiredoxin 2
-
 Homo sapiens
1.11.1.24 Prx2
-
 Homo sapiens