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Literature summary extracted from

  • Kaczocha, M.; Hermann, A.; Glaser, S.T.; Bojesen, I.N.; Deutsch, D.G.
    Anandamide uptake is consistent with rate-limited diffusion and is regulated by the degree of its hydrolysis by fatty acid amide hydrolase (2006), J. Biol. Chem., 281, 9066-9075.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.4 CAY10400
-
 Rattus norvegicus
3.5.1.4 OMDM2 0.01 mM, 16% inhibition Rattus norvegicus
3.5.1.4 UCM707
-
 Rattus norvegicus
3.5.1.4 URB597
-
 Rattus norvegicus
3.5.1.4 VDM11
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.1.4 anandamide + H2O Rattus norvegicus
-
 arachidonic acid + ethanolamine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.4 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.1.4 RBL-2H3 cell basophilic leukemia cell. Anandamide uptake is consistent with rate-limited diffusion and is regulated by the degree of its hydrolysis by fatty acid amide hydrolase Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.4 anandamide + H2O
-
 Rattus norvegicus arachidonic acid + ethanolamine
-
 ?

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.5.1.4 0.0000005
-
-
 Rattus norvegicus CAY10400
3.5.1.4 0.000002
-
-
 Rattus norvegicus URB597
3.5.1.4 0.005
-
-
 Rattus norvegicus VDM11
3.5.1.4 0.05
-
-
 Rattus norvegicus UCM707