EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
1.3.1.22 | A207D | the mutation is associated with 5alpha-reductase type 2 deficiency | Homo sapiens |
1.3.1.22 | A49T | the mutation is associated with 5alpha-reductase type 2 deficiency | Homo sapiens |
1.3.1.22 | C133G | the mutation is associated with 5alpha-reductase type 2 deficiency | Homo sapiens |
1.3.1.22 | G196S | the mutation is associated with 5alpha-reductase type 2 deficiency | Homo sapiens |
1.3.1.22 | G34W | the mutation is associated with 5alpha-reductase type 2 deficiency | Homo sapiens |
1.3.1.22 | W53X | the mutation is associated with 5alpha-reductase type 2 deficiency | Homo sapiens |
1.3.1.22 | Y235F | the mutation is associated with 5alpha-reductase type 2 deficiency | Homo sapiens |
1.3.99.5 | A207D | the mutation is associated with the occurrence of steroid 5alpha-reductase deficiency | Homo sapiens |
1.3.99.5 | C133G | the mutation is associated with the occurrence of steroid 5alpha-reductase deficiency | Homo sapiens |
1.3.99.5 | G196S | the mutation is associated with the occurrence of steroid 5alpha-reductase deficiency | Homo sapiens |
1.3.99.5 | G34W | the mutation is associated with the occurrence of steroid 5alpha-reductase deficiency | Homo sapiens |
1.3.99.5 | W53X | the nonsense mutation is associated with the occurrence of steroid 5alpha-reductase deficiency | Homo sapiens |
1.3.99.5 | Y235F | the mutation is associated with the occurrence of steroid 5alpha-reductase deficiency | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.1.22 | testosterone + NADPH + H+ | Homo sapiens | - |
5alpha-dihydrotestosterone + NADP+ | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.3.1.22 | Homo sapiens | - |
- |
- |
1.3.99.5 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.3.99.5 | blood | - |
Homo sapiens | - |
1.3.99.5 | leukocyte | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.1.22 | testosterone + NADPH + H+ | - |
Homo sapiens | 5alpha-dihydrotestosterone + NADP+ | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.3.1.22 | 5alphaR type 2 | - |
Homo sapiens |
1.3.1.22 | SRD5A2 | - |
Homo sapiens |
1.3.1.22 | steroid 5alpha reductase type 2 | - |
Homo sapiens |
1.3.99.5 | 5alpha-R | - |
Homo sapiens |
1.3.99.5 | steroid 5alpha-reductase type 2 | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.3.1.22 | NADPH | - |
Homo sapiens |