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Literature summary extracted from

  • Frank, J.; Lornejad-Schaefer, M.R.; Schoeffl, H.; Flaccus, A.; Lambert, C.; Biesalski, H.K.
    Inhibition of heme oxygenase-1 increases responsiveness of melanoma cells to ALA-based photodynamic therapy (2007), Int. J. Oncol., 31, 1539-1545.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.14.14.18 additional information the enzyme is induced by 5-aminolevulinic acid, the activation is reduced to 29% by gene silencing with siRNA, overview Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.14.18 quantitative enzyme expression analysis Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
1.14.14.18 additional information enzyme downregulation by expression of HO-1 siRNA in WM451Lu cells, reverses the upregulating effect of 5-aminolevulinic acid, oerview Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.14.18 Sn-protoporphyrin IX i.e. SNPPIX Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.18 Homo sapiens P09601
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.18 melanoma cell quantitative HO-1 expression analysis Homo sapiens
-
1.14.14.18 WM-451Lu cell quantitative HO-1 expression analysis Homo sapiens
-

Synonyms

EC Number Synonyms Comment Organism
1.14.14.18 heme oxygenase-1
-
 Homo sapiens
1.14.14.18 HO-1
-
 Homo sapiens