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Literature summary extracted from
- Congenital hypoaldosteronism (2008), Indian Pediatr., 45, 695-697.
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.15.5 | corticosterone + reduced adrenal ferredoxin + O2 | Homo sapiens | - |
18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O | - |
? |  |
| 1.14.15.5 | additional information | Homo sapiens | reduced enzyme activity occurs in hyponatremia and hyperkalemia due to an isolated aldosterone biosynthesis defect, the phenotype can be rescued by a fludrocortisone replacement therapy, overview | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.15.5 | Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.15.5 | corticosterone + reduced adrenal ferredoxin + O2 | - |
Homo sapiens | 18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O | - |
? | |
| 1.14.15.5 | additional information | reduced enzyme activity occurs in hyponatremia and hyperkalemia due to an isolated aldosterone biosynthesis defect, the phenotype can be rescued by a fludrocortisone replacement therapy, overview | Homo sapiens | ? | - |
? | |
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Release 2023.1 (January 2023)
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