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Literature summary extracted from

  • Maintz, L.; Schwarzer, V.; Bieber, T.; van der Ven, K.; Novak, N.
    Effects of histamine and diamine oxidase activities on pregnancy: a critical review (2008), Hum. Reprod. Update, 14, 485-495.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.4.3.22 medicine the balance between histamine and DAO seems to be crucial for an uncomplicated course of pregnancy. Reduced DAO activities are found in multiple heterogeneous complications of pregnancy such as diabetes, threatened and missed abortion and trophoblastic disorders. Low activities of the histamine-degrading enzyme DAO might indicate high-risk pregnancies, although high intra- and interindividual variations limit its value as a screening tool Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.22 Homo sapiens
-
-
-
4.1.1.22 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.22 placenta
-
 Homo sapiens
-
4.1.1.22 placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.22 L-histidine
-
 Homo sapiens histamine + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.22 DAO
-
 Homo sapiens
4.1.1.22 HDC
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.22 pyridoxal 5'-phosphate
-
 Homo sapiens