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Literature summary extracted from

  • Aranda, R.; Domenech, E.; Rus, A.D.; Real, J.T.; Sastre, J.; Vina, J.; Pallardo, F.V.
    Age-related increase in xanthine oxidase activity in human plasma and rat tissues (2007), Free Radic. Res., 41, 1195-1200.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.17.3.2 xanthine + H2O + O2 Rattus norvegicus old animals show higher enzyme expression and activity than young rats which promotes a worse prognosis for patients with chronic heart failure due to the increased contents of risk factor urate, overview urate + H2O2
-
 ?
1.17.3.2 xanthine + H2O + O2 Homo sapiens old persons show higher enzyme expression and activity than young persons which promotes a worse prognosis for patients with chronic heart failure due to the increased contents of risk factor urate, overview urate + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.17.3.2 Homo sapiens
-
-
-
1.17.3.2 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.17.3.2 aorta wall Rattus norvegicus
-
1.17.3.2 blood positive correlation between plasma xanthine oxidase and age of the individual Homo sapiens
-
1.17.3.2 plasma positive correlation between plasma xanthine oxidase activity and expression and age of the animal Rattus norvegicus
-
1.17.3.2 skeletal muscle positive correlation between plasma xanthine oxidase activity and expression and age of the animal Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.17.3.2 additional information
-
-
 Homo sapiens
1.17.3.2 additional information
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.3.2 xanthine + H2O + O2
-
 Homo sapiens urate + H2O2
-
 ?
1.17.3.2 xanthine + H2O + O2
-
 Rattus norvegicus urate + H2O2
-
 ?
1.17.3.2 xanthine + H2O + O2 old animals show higher enzyme expression and activity than young rats which promotes a worse prognosis for patients with chronic heart failure due to the increased contents of risk factor urate, overview Rattus norvegicus urate + H2O2
-
 ?
1.17.3.2 xanthine + H2O + O2 old persons show higher enzyme expression and activity than young persons which promotes a worse prognosis for patients with chronic heart failure due to the increased contents of risk factor urate, overview Homo sapiens urate + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.17.3.2 More formerly EC 1.1.3.22 Homo sapiens
1.17.3.2 More formerly EC 1.1.3.22 Rattus norvegicus