Literature summary extracted from

Coyoy, A.; Valencia, A.; Guemez-Gamboa, A.; Moran, J.
Role of NADPH oxidase in the apoptotic death of cultured cerebellar granule neurons (2008), Free Radic. Biol. Med., 45, 1056-1064.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.6.3.1	4-(2-aminoethyl)benzenesulfonyl fluoride	significantly reduces reactive oxygen species production, NADPH oxidase activity, and all the apoptotic events, and cell death induced by both 5 mM KCl and staurosporin	Rattus norvegicus
1.6.3.1	diphenylene iodonium	significantly reduces reactive oxygen species production, NADPH oxidase activity, and all the apoptotic events, and cell death induced by both 5 mM KCl and staurosporin	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.6.3.1	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.6.3.1	neuron	in primary cultures of cerebellar granule neuron, expression of the components of NADPH oxidase proteins, p40phox, p47phox and p67phox,and p22phox, as well as three homologues of the catalytic subunit, NOX1, 2, and 4	Rattus norvegicus	-

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Release 2023.1 (January 2023)