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Literature summary extracted from

  • Schmidt, M.; Drgon, T.; Bowers, B.; Cabib, E.
    Hyperpolarized growth of Saccharomyces cerevisiae cak1P212S and cla4 mutants weakens cell walls and renders cells dependent on chitin synthase 3 (2008), FEMS Yeast Res., 8, 362-373.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.4.1.16 analysis the chs3 gene encoding the chitin synthase 3 is used for synthetically lethality screening for mutation determination, overview Saccharomyces cerevisiae

Protein Variants

EC Number Protein Variants Comment Organism
2.4.1.16 additional information screening for mutations synthetically lethal with chs3 in the indicator strain ECY46-4-1B, the thin cell wall phenotype is caused by a mutation of the Cdc28-activating kinase CAK1 gene, phenotype, reduced or increased CSIII activity, overview Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.16 membrane
-
 Saccharomyces cerevisiae 16020
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.16 Saccharomyces cerevisiae P29465 gene chs3coding for the catalytic subunit of the chitin synthase III
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.16 UDP-GlcNAc + GlcNAc
-
 Saccharomyces cerevisiae UDP + N-acetyl-beta-D-glucosaminyl-(1,4)-N-acetyl-beta-D-glucosamine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.16 chitin synthase 3
-
 Saccharomyces cerevisiae
2.4.1.16 chitin synthase III
-
 Saccharomyces cerevisiae
2.4.1.16 CSIII
-
 Saccharomyces cerevisiae

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.16 30
-
 assay at Saccharomyces cerevisiae

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.16 8
-
 assay at Saccharomyces cerevisiae